Oral contraceptives, rheumatoid arthritis, and androgens
نویسندگان
چکیده
منابع مشابه
Androgens in active rheumatoid arthritis
Neither hormone receptor genes nor plasma androgens seem significantly altered in female subjects before they became affected by rheumatoid arthritis (RA) and, therefore, do not seem to play a role as risk factors for its development. However, serum testosterone levels are inversely correlated with RA activity and dehydro-epiandrosterone sulfate (DHEAS) plasma levels are inversely correlated wi...
متن کاملRheumatoid arthritis, the contraceptive pill, and androgens.
Evidence is accumulating that low androgen concentrations are a cause of rheumatoid arthritis. This would explain a number of established features of the epidemiology of the disease. These include: (a) the variation of disease activity with pregnancy; (b) the variation of age at onset by sex; (c) the variation by sex with HLA-B15; (d) the association with bone mineral density; and (e) the diffe...
متن کاملOral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study
OBJECTIVES To study whether oral contraceptive (OC) use or breastfeeding (BF) influence the risk of rheumatoid arthritis (RA), stratifying the cases by presence/absence of anticitrullinated protein antibodies (ACPA), and whether these factors interact with known risk factors in the development of ACPA-positive RA. METHODS Women aged ≥18 years, participants in the population-based case-control...
متن کاملMeta-analysis of oral contraceptives and rheumatoid arthritis risk in women
BACKGROUND AND OBJECTIVES Epidemiological investigations of the relationship between oral contraceptives and rheumatoid arthritis (RA) risk have reported controversial results. Therefore, a meta-analysis of case-control or cohort studies was performed to evaluate the role of oral contraceptives in relation to risk of developing RA. METHODS Eligible studies were identified from databases PubMe...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2003
ISSN: 0003-4967
DOI: 10.1136/ard.62.3.279